The busy port of Santos is the gateway to cosmopolitan São Paulo, a vast metropolis that is home to some 20 million people, making it the third largest city on earth. The urban sprawl may not be to everyone’s taste, but for fans of big city life there is plenty to see and do, with a lively cultural scene and a host of world class restaurants.

The city of Itajaí is situated in the southern Brazilian state of Santa Catarina, known for its sweeping sandy beaches and lush Atlantic forest. The region also has an intriguing German heritage thanks to the many immigrants who settled here during the 19th and early 20th centuries.

Located just across the Río de la Plata from Buenos Aires, Uruguay’s underrated capital is a cosmopolitan and eclectic mix of colourful colonial architecture and high rise modernity. The 14-mile waterfront promenade, La Rambla, is a popular and pleasant place to be on a summer’s evening.

The streets of Buenos Aires are redolent of a grand old European capital, lined with elegant architecture that wouldn’t look out of place in Madrid or Paris. There is also plenty of Latin passion on display: Argentina is the home of tango, that most electrifying of dances, and has played host to countless revolutions over the years.

The upmarket Uruguayan beach resort of Punta del Este is where the A-listers come to party, with a reputation as the Saint Tropez of South America. The town also has an arty side, typified by intriguing sculptures such as the giant concrete fingers emerging from the beach at Playa Brava.

The rugged and windswept Falkland Islands make for a fascinating stop on the way to or from Antarctica. Over 80% of the population lives in the capital, Stanley, though humans are far outnumbered by other creatures, including penguins, sea lions and albatrosses.

Perched on the ragged southern edge of Argentina, where the snow-capped Andes fall away into the churning sea, Ushuaia has a frontier town feel to it, and serves as the base for expeditions into the icy waters of Antarctica.

The weather-beaten city of Punta Arenas is a laid back and welcoming place, in spite of its inhospitable location on the shores of the Strait of Magellan. Nearby attractions include penguin colonies and the dramatic scenery of Torres del Paine National Park, while beyond the horizon lie the frozen wastes of Antarctica.

Puerto Chacabuco is situated close to the Aysén Fjord and serves as a gateway to the Laguna San Rafael National Park, a UNESCO Biosphere Reserve. Amongst the lush forests, waterfalls and lagoons you have the chance to spot wildlife including marine otters, giant condors and Chilean dolphins.

Puerto Montt is the capital of the Chilean Lake District, spread out around a wide bay against a backdrop of snow-capped volcanoes. This wild region offers a host of outdoor activities, including mountain hikes, kayaking, white water rafting, fishing, zip lining and cycling.