Renowned for its food, its misty mornings and its vertiginous streets, cosmopolitan San Francisco is quite unlike any other American city. Highlights include the iconic Golden Gate Bridge, the delightful waterfront and the bohemian quarter of Haight Ashbury.

Astoria is the oldest city west of the Rockies, situated on the picturesque Oregon coast where the Columbia river meets the Pacific Ocean. This bustling port town is sometimes known as ‘Little San Francisco’, with handsome Victorian architecture, a proud fishing heritage and a buzzing, creative vibe.

Victoria is the capital of British Columbia and Canada’s westernmost city, with a distinctly English feel that occasionally borders on the twee. It’s a very walkable city, with handsome 19th century architecture, verdant parks and a lively harbour, and, this being Canada, the great outdoors is never far away.

Cosmopolitan Vancouver is a city that rewards exploration, an eminently liveable place and an easy gateway to the natural beauty of British Columbia. The culinary scene here is a particular draw, with seafood galore and some fantastic Asian restaurants.

Sitka was founded by Russian fur traders in 1799 as the city of New Archangel, and there is still a discernible Russian influence here, including the distinctive St Michael’s Orthodox Cathedral. The town also enjoys spectacular natural surroundings, facing the Pacific Ocean and dramatic Mount Edgecumbe.

Situated at the northern end of the Inside Passage, Skagway is an impressively well preserved former gold rush town, with a charming historic centre that’s easy to explore on foot. Popular activities include hiking to the pristine Lower Dewey Lake and the scenic train ride along the old gold rush route.

Ketchikan is a great introduction to Alaska’s natural attractions, situated at the foot of towering Deer Mountain and within easy reach of the Misty Fjords. The colourful wooden buildings of Creek Street, the old red light district, are a reminder of Ketchikan’s former status as a rough and ready frontier town; these days, things are rather more civilised!