Renowned for its food, its misty mornings and its vertiginous streets, cosmopolitan San Francisco is quite unlike any other American city. Highlights include the iconic Golden Gate Bridge, the delightful waterfront and the bohemian quarter of Haight Ashbury.

Astoria is the oldest city west of the Rockies, situated on the picturesque Oregon coast where the Columbia river meets the Pacific Ocean. This bustling port town is sometimes known as ‘Little San Francisco’, with handsome Victorian architecture, a proud fishing heritage and a buzzing, creative vibe.

Victoria is the capital of British Columbia and Canada’s westernmost city, with a distinctly English feel that occasionally borders on the twee. It’s a very walkable city, with handsome 19th century architecture, verdant parks and a lively harbour, and, this being Canada, the great outdoors is never far away.

Cosmopolitan Vancouver is a city that rewards exploration, an eminently liveable place and an easy gateway to the natural beauty of British Columbia. The culinary scene here is a particular draw, with seafood galore and some fantastic Asian restaurants.

Ketchikan is a great introduction to Alaska’s natural attractions, situated at the foot of towering Deer Mountain and within easy reach of the Misty Fjords. The colourful wooden buildings of Creek Street, the old red light district, are a reminder of Ketchikan’s former status as a rough and ready frontier town; these days, things are rather more civilised!

Sitka was founded by Russian fur traders in 1799 as the city of New Archangel, and there is still a discernible Russian influence here, including the distinctive St Michael’s Orthodox Cathedral. The town also enjoys spectacular natural surroundings, facing the Pacific Ocean and dramatic Mount Edgecumbe.

The tiny city of Seward, home to just 3,000 people, enjoys a spectacular setting on the edge of Resurrection Bay, on Alaska’s southern coast. Surrounded by the mountains and forests of the Kenai Fjords National Park, it’s a great base for exploring the Harding Ice Field and the stunning scenery of the Kenai Peninsula.

Kodiak is known as Alaska’s ‘Emerald Isle’ thanks to the lush green countryside, a landscape crisscrossed by gushing salmon-filled streams that provides a home to around 3,000 Kodiak bears, the world’s largest. Ships dock in Kodiak city, an important fishing port with a fascinating Russian heritage.

Dutch Harbor is the port that serves the city of Unalaska, and is known for the hardy fishermen who brave the turbulent, icy seas off the Aleutian Islands. Points of interest include the remains of defensive fortifications built during the Second World War and the striking Russian Orthodox church.

The city of Aomori, at the northern tip of Honshu island, is best known for its summer Nebuta Matsuri festival, which lights up the streets every August. There is still plenty to see during the rest of the year, including elegant Hirosaki Castle, pretty Lake Towada and the Seiryu-ji Temple, home of the largest Buddha statue in Japan.

Situated at the southern tip of Hokkaido, Hakodate was one of the first Japanese ports to open up to international trade in the 19th century, and a scattering of European-style buildings remain. Take a ride on the historic streetcar, tuck into delicious seafood or enjoy a revitalising dip in an onsen (hot spring).

In a state of constant renewal and forever looking to the future, densely populated Tokyo is a dazzling introduction to Japan and its utterly unique culture. With more neon than Las Vegas and more Michelin stars than Paris, it’s a real assault on the senses.

Shimizu is one of the most spectacular ports in Japan, a sweeping bay in the shadow of the iconic Mount Fuji. You can spend some time admiring the views and wandering through peaceful pine groves, or visit the unique Shimizu Sushi Museum at the S-Pulse Dream Plaza shopping mall.

Small in size and cosmopolitan in its outlook, Kobe is a thoroughly pleasant city with a long and distinguished history as one of Japan’s main trading ports. Kobe’s past as a commercial hub is reflected in its architecture, with a number of unusually European-looking houses, as well as a charming, if slightly touristy, Chinatown.

On 6 August 1945 the world witnessed the terrifying power of nuclear weapons for the first time, unleashed on the unsuspecting Japanese city of Hiroshima. The modern city's sobering Peace Memorial Park commemorates that fateful day, which left more than 140,000 dead.

The city of Miyazaki sits on the southeastern coast of Kyushu, the warmest of Japan’s main islands, and it’s a popular spot for domestic tourists. Worthwhile excursions include the historic town of Obi, known as ‘Little Kyoto’, and laid back Aoshima island, home to a picturesque shrine.

Keelung is a fairly unremarkable port city close to Taipei, Taiwan’s capital. Taipei draws on an interesting mix of Chinese, Japanese and Western influences, and is home to attractive temples, a burgeoning street food scene and Taipei 101, which was the world's tallest building until it was eclipsed by Dubai's Burj Khalifa in 2010.

Hong Kong is a striking mix of ancient and modern, Chinese and British, and there is a lot more to the city than just skyscrapers and high finance. It's also a fantastic destination for foodies, a melting pot of culinary influences from around Asia and beyond.

Nha Trang is Vietnam’s premier beach destination, on a stunning bay dotted with idyllic islands. The main attraction is the laid back seaside atmosphere, but there are also a few noteworthy cultural sites, including the ancient Po Nagar Cham Towers, which were built between the 7th and 12th centuries.

Saigon, as it was known then, was the capital of the South during the Vietnam War, and American-style capitalism has been embraced more enthusiastically here than in the North, with a clutch of shining skyscrapers standing as testament to Vietnam’s surging economic growth.

Singapore’s heritage as an important trading post means that there is a real cultural mix, with four official languages: English, Chinese, Malay and Tamil. Step away from the gleaming towers and you’ll find yourself transported into another world amongst the intoxicating streets of Chinatown and Little India.

Indonesia’s capital is noisy, chaotic and choked with some of the worst traffic in Asia, a sprawling megacity that’s home to over 10 million people. If you can get past all of that then Jakarta has plenty to offer, with the country’s best museums and restaurants, an atmospheric old harbour and a rich mix of cultures from all over the Indonesian archipelago.

The beaches, spectacular volcanic scenery and lush green rice terraces lend Bali a natural beauty that seems to dovetail perfectly with the island’s distinct Hindu culture, which adorns the landscape with stunning temples.

More of a large town than a city, Darwin is less about what’s contained within the city limits and more about the huge expanse of wild landscape that’s outside it. Closer to Jakarta than Sydney, the city really does feel remote in its tropical perch.

Named after the British naval officer Sir Fairfax Moresby, Papua New Guinea’s capital is the biggest city in the South Pacific. It’s a gritty place that has its fair share of problems, but it’s also home to some interesting sights, including the striking Parliament Haus building and the National Botanical Gardens.

Alotau is the capital of Milne Bay province, on the remote eastern tip of mainland Papua New Guinea. Milne Bay was the scene of heavy fighting during the Second World War, and today you can dive amongst the wreckage left behind. Alotau also serves as a base for visiting the nearby islands, including the fascinating Trobriand archipelago.

Cairns is a buzzing tourist hub, gateway to the Great Barrier Reef and the Daintree Rainforest. A snorkelling trip out to the reef is the most obvious excursion to take here, but other options include riding the Skyrail cableway over the rainforest canopy or swimming in the croc-free saltwater lagoon.

Sunny Townsville is a great introduction that everything that Queensland has to offer, sandwiched between palm-fringed beach and rugged outback. It’s a friendly and walkable city, with a fascinating museum and an aquarium that gives you a taste of the Great Barrier Reef.

One or our favourite cities in the world, we love pretty much everything about Sydney. Offering outdoor living at its best, the city is known for the excellent beaches but offers so much more, including a thriving and varied food scene inspired by Asian and European flavours.

The beautiful Bay of Islands is scattered with some 150 undeveloped islands, an idyllic landscape of bright skies, secluded beaches and clear blue waters. The bay was also the site of the first permanent British settlement in New Zealand, and it was here that the Treaty of Waitangi was signed in 1840 between the British Crown and the Maori chiefs.