Bordeaux sits at the centre of the world's most famous wine region, and is home to a beguiling blend of beautiful buildings, sophisticated gastronomy and high culture. It's a marvellous place to spend some time, whether it's a day sampling wines, an evening at the opera or a night on the tiles.

It’s not so long ago that Bilbao was a grim and unappealing place, scarred by heavy industry, but the Basque Country’s biggest city has reinvented itself as a cultural hub since the opening of the shimmering Guggenheim Museum in 1997.

Gijón is the largest city in the Asturias region of northern Spain, an important industrial port but also a lively and youthful place, ideally positioned for exploring the Costa Verde. The most interesting area is the historic fishing village of Cimadevilla, which sits on a peninsula that divides the bay in two.

La Coruña is the largest city in Galicia, a beautiful region of lush green countryside and wild, windswept beaches. Historical sights of note include the Tower of Hercules, a UNESCO-listed Roman lighthouse, and the city is also home to some great seafood restaurants.

Blessed with a dramatic setting on the steep banks of the river Douro, Portugal’s second city is currently enjoying something of a renaissance, and is best known as the home of the country’s most famous export, port wine.

Spread across steep hillsides that overlook the Rio Tejo, Lisbon’s colourful cityscape includes Gothic cathedrals, majestic monasteries and quaint museums. But for many the best times will be had wandering the narrow lanes of Lisbon’s lovely backstreets, with their great local food, wine and music.

The crumbling, sun-baked seafront city of Cádiz is said to be the oldest continuously inhabited settlement in the western world, founded by the Phoenicians around 1100 BC. Although the city lacks any obvious landmarks, it’s rich in atmosphere, and plays host to one of Spain’s most colourful carnivals.

Málaga boasts plenty of chic restaurants and bars where you can ease into the rhythms of life in southern Spain, before exploring sights including the intriguing, unfinished Gothic cathedral, and a museum devoted to the city's most famous son, Pablo Picasso.

Cartagena was founded by the Carthaginians around 227 BC, who named it after their home city in North Africa. These days the city is best known for its well-preserved Roman theatre, which was remarkably only discovered in 1987, in spite of its location in the centre of town.

Spain’s third city is a dazzling destination that combines historic architecture, cutting edge design and an inviting stretch of beach. Don’t miss the futuristic City of Arts and Sciences, designed by local architect Santiago Calatrava, or the old riverbed, now a delightful park.

Mallorca is renowned for its beaches, ranging from big, bustling resorts to small, secluded coves. The island interior offers ruggedly beautiful scenery and quaint little towns, while the charming capital, Palma, boasts an attractive old quarter dominated by the imposing Gothic cathedral.