Toulon is not the sort of place you would expect to find on the Côte d’Azur, a gritty port city that’s home to France’s most important naval base. It’s not completely without charm, however, and for some travellers it may come as a breath of fresh air after the glitz of the Riviera. For the best view, take the cable car to the top of Le Faron mountain.

Nice enjoys a marvellous setting on one of the most glorious stretches of the Côte d’Azur, the sweeping Bay of Angels, so it’s no wonder that tourists have been flocking here since the 19th century.

One of the world’s great cities, Rome continues to dazzle and delight visitors with a potent mix of architectural marvels, continent-defining history and buzzing nightlife. The Colosseum, the Vatican and the Forum are among the big ticket items, with the crowds to match, though in truth you will find history around almost every corner.

The UNESCO World Heritage-listed centre of Naples rewards exploration, and in addition to the many cultural treasures waiting to be unearthed Neapolitans are rightly proud of their food; this is where you’ll find the best pizza in Italy. The city also acts as a gateway to the fascinating remains of Pompeii and Herculaneum, and the beautiful Amalfi coast.

Busy, noisy and a little bit scruffy, Catania is Sicily’s second city, poised perilously in the shadow of Mount Etna. In recent years gentrification has taken hold, and the city’s many beautiful palazzi and baroque churches have been restored to their former glory. Eating out here is also a real treat.

Rugged Kefalonia is the largest of the Ionian islands, and remains unspoilt by tourism despite earning fame as the setting for ‘Captain Corelli’s Mandolin’. The island rewards exploration, with some splendid beaches and lovely little villages, and the vineyards here produce some excellent wines.

Chania, Crete’s second city, is an alluring blend of architectural styles. The jumble of streets that make up the Venetian old town are remarkably intact, and there are plenty of reminders too of the two centuries of Ottoman rule, such as the imposing harbourfront Mosque of the Janissaries.

The volcanic island of Santorini (known officially as Thira) is one of the most spectacularly beautiful in the Mediterranean. The pretty village of Oia, with its whitewashed houses and windmills tumbling down the hillside, is particularly photogenic.

Athens is a city awash with historical and cultural significance, but it's much more than an open air museum; this is a dynamic, bustling metropolis, and a place where history is still very much unfolding.

The Turkish port of Kusadasi is the gateway to Ephesus, one of the most spectacular archaeological sites in the Eastern Mediterranean. This was the Roman capital of Asia Minor, and the remains constitute the most complete classical city in Europe.

Istanbul is the place where East meets West, where Asia Minor reaches out across the Bosphorus and almost touches Europe, and the city remains a bristling, bustling cultural melting pot, the skyline dotted with magnificent minarets and domes.

The Aegean island of Bozcaada, also known as Tenedos, is a popular weekend and summer escape for residents of Istanbul. The main settlement, Bozcaada Merkez, has an atmospheric Greek quarter full of colourful houses, while elsewhere on the island you'll find vineyards, beaches and an impressive castle.

The Turkish port of Kusadasi is the gateway to Ephesus, one of the most spectacular archaeological sites in the Eastern Mediterranean. This was the Roman capital of Asia Minor, and the remains constitute the most complete classical city in Europe.

Sun-kissed Rhodes, the largest of the Dodecanese islands, is steeped in history; the medieval heart of Rhodes Town was once home to the crusading Knights of St John, and later fell to the Ottoman sultan Suleiman the Magnificent. The hillside village of Lindos, with its pretty whitewashed houses, is another highlight.

The buzzing city of Limassol is southern Cyprus’ main port, an important commercial hub that overflows with bars, restaurants and tavernas. It’s also home to a pleasant old town and medieval castle, and serves as an excellent base for exploring the nearby Troodos mountains.

Haifa is Israel’s third city, a bustling and multicultural place where six different faiths live side by side. The city is the spiritual centre of the Baha’i Faith, and the beautiful Baha’i Gardens are a must-see. Many cruise visitors opt to skip Haifa and take an excursion to Jerusalem and Bethlehem, two to three hours’ drive away.

Aqaba is Jordan’s principal beach resort, situated on the Red Sea coast close to the Israeli border. The main attraction in Aqaba itself is the incredible diving, though many visitors will choose to instead use the port as a jumping off point for the 'Rose City' of Petra and the desert landscapes of Wadi Rum.

Safaga is the nearest sea port to Luxor, and ships often stop here overnight to give you time to see everything. Prepare to be amazed – the thin belt of greenery along the banks of the Nile gives Luxor a lush setting for an extraordinary collection of tombs and temple complexes that hint at the magnificence of this former Ancient Egyptian capital.

The port city of Jeddah has long been a cultural crossroads, serving as the gateway to Mecca for pilgrims making the Hajj, and there's a cosmopolitan feel here that other Saudi cities lack. The old Al-Balad neighbourhood is home to the city’s most characterful buildings, while the buzzing Corniche promenade is a great spot for people watching.

Oman’s capital is low-rise and laid back, a far cry from the towering bling of Dubai and Abu Dhabi. Take a stroll along the waterfront Corniche promenade, soak up the sun on one of the excellent beaches, or explore the mosques and forts of the atmospheric old quarter.