Greece’s bustling second city has a rich history, shaped by Roman, Byzantine and Ottoman rule, and was once home to a large Jewish community. Sadly many of Thessaloniki’s historic buildings were destroyed by a fire in 1917, but the famous White Tower survives, along with the city’s vibrant, multicultural spirit.

The bustling port of Volos sits on the site of the ancient city of Iolkos, the mythological home of Jason and the Argonauts. The modern city has plenty of interesting museums and churches, along with a pleasant waterfront lined with restaurants.

The Turkish port of Kusadasi is the gateway to Ephesus, one of the most spectacular archaeological sites in the Eastern Mediterranean. This was the Roman capital of Asia Minor, and the remains constitute the most complete classical city in Europe.

Glamorous Mykonos is the most popular of the Cyclades islands, well known as a haunt of the rich and the famous. It’s also the gateway to the nearby island of Delos, home to one of the most important archaeological sites in Greece.

Paros gleams with a classic Cycladic colour palette of whitewashed houses and blue-domed churches, and is famous for its ancient marble quarries, which provided the raw material for the Venus de Milo. The island is also home to some great restaurants, peaceful inland villages and lovely beaches.

The volcanic island of Santorini (known officially as Thira) is one of the most spectacularly beautiful in the Mediterranean. The pretty village of Oia, with its whitewashed houses and windmills tumbling down the hillside, is particularly photogenic.

The island of Spetses lies just off the coast of the Peloponnese, and is popular as a second home for well-to-do Athenians. Wander the streets of charming Spetses Town and you’ll find some excellent restaurants, while the surrounding countryside is a verdant landscape of pine forest and gently rolling hills.

Nafplion is one of the most beautiful cities on the Greek mainland, situated on the Argolic Gulf overlooked by the imposing Palamidi Fortress. The narrow streets of the old town are home to a beguiling mix of Venetian, Turkish and Greek architecture, while just offshore is the little island castle of Bourtzi.

Athens is a city awash with historical and cultural significance, but it's much more than an open air museum; this is a dynamic, bustling metropolis, and a place where history is still very much unfolding.

The beautiful Byzantine town of Monemvasia is dramatically located on a steep chunk of rock, originally a coastal headland until an earthquake in AD 375 turned it into an island. Nowadays access is via a narrow causeway, and the pretty streets of the medieval citadel are home to more churches than people.

Chania, Crete’s second city, is an alluring blend of architectural styles. The jumble of streets that make up the Venetian old town are remarkably intact, and there are plenty of reminders too of the two centuries of Ottoman rule, such as the imposing harbourfront Mosque of the Janissaries.

Palermo is an acquired taste; noisy, chaotic and rather grimey in places. But there’s something quite intoxicating about the crumbling facades and the bustling markets, and the Arabesque style of many of the buildings hints at Sicily’s historical role as a stepping stone between Europe and North Africa.

The UNESCO World Heritage-listed centre of Naples rewards exploration, and in addition to the many cultural treasures waiting to be unearthed Neapolitans are rightly proud of their food; this is where you’ll find the best pizza in Italy. The city also acts as a gateway to the fascinating remains of Pompeii and Herculaneum, and the beautiful Amalfi coast.

One of the world’s great cities, Rome continues to dazzle and delight visitors with a potent mix of architectural marvels, continent-defining history and buzzing nightlife. The Colosseum, the Vatican and the Forum are among the big ticket items, with the crowds to match, though in truth you will find history around almost every corner.

The attractive, oceanfront capital of Corsica was the birthplace of the island’s most famous son, Napoleon Bonaparte. You can find out more about the emperor at his childhood home, the Maison Bonaparte, which is now a museum.

Ever since Brigitte Bardot put Saint Tropez on the map with the seminal ‘And God Created Woman’ in 1956, this diminutive fishing village on the French Riviera has been a magnet for the international glitterati.

Renowned for its casino, its Grand Prix and its oligarch-friendly tax policies, Monte Carlo is glamour and hedonism personified, with a price tag to match. This little principality enjoys a lovely setting, the villas and penthouses tumbling down the hillside towards the sweeping blue expanse of the Mediterranean.