Basel lies where Switzerland, France and Germany meet, a sophisticated and multicultural city with a picturesque setting astride the river Rhine. The medieval Old Town is exceptionally well preserved, best appreciated from the summit of the hilltop cathedral, which offers incredible views across the city.

Breisach is a small town on the western fringe of the Black Forest, separated from the French region of Alsace by a bend in the river Rhine. This proximity to France is reflected in a vibrant food and wine scene, and architectural highlights include the hilltop St Stephen's cathedral.

Strasbourg is the capital of France’s Alsace region, right next to the border with Germany, and there is a tangible Germanic influence that sets the city a little apart from the rest of France. Highlights include the beautiful Gothic cathedral, the old town’s fairytale half-timbered houses, and the pictureque canals of the Petite France district.

Situated near the confluence of the Rhine and Neckar rivers, Mannheim is an important industrial centre with a lively cultural scene. It’s also conveniently located for exploring the pretty town of Heidelberg and the wine growing region around Nierstein.

The pretty little town of Rüdesheim, situated on a bend in the Rhine surrounded by vineyards, is a popular destination for travellers looking for a slice of quintessentially German village life. The Drosselgasse, a narrow cobbled lane flanked by old timber frame buildings, is particularly atmospheric.

One of the prettiest towns in the Moselle valley, Cochem is a popular stop for river cruise ships. With an old town full of half-timbered houses and a castle perched on a hill it’s a quintessentially German scene, and the riverside promenade is lovely during the sunny summer months.

The pretty town of Bernkastel lies in the heart of the Moselle wine region, and is known for its excellent dry whites based on the Riesling grape. The picturesque half-timbered houses of the old town date back to the Middle Ages, and there are plenty of wine taverns where you can enjoy a glass or two.

Koblenz was founded by the Romans, who valued the city’s strategically important location where the Rhine and Moselle rivers meet. Rebuilt from the rubble of the Second World War, modern Koblenz has a pleasant and relaxed atmosphere, and serves as a gateway to the Romantic Rhine.

Nijmegen is one of the oldest cities in the Netherlands, and was the site of a Roman military camp in the 1st century BC. Nowadays it’s a bustling city with a charming medieval centre, home to Holland’s oldest shopping street and the fascinating Freedom Museum, which documents the Dutch experience during the Second World War.

Antwerp is a city bound up with the arts, once home to the likes of Rubens and Van Dyck, and more recently carving out a reputation as the fashion capital of Belgium. It’s also a magnet for shopaholics, with designer boutiques and jewellers galore.