Bamberg’s eye-catching, UNESCO-listed old town is one of the most beautiful in all of Germany. The city was briefly capital of the Holy Roman Empire, and the city centre is still dominated by the 13th century cathedral. There are also plenty of breweries, and you shouldn’t leave without trying Bamberg’s famous smoked beer.

The handsome town of Würzburg, situated on the river Main between Nuremberg and Frankfurt, was ruled for centuries by a succession of powerful prince-bishops. Although much of the city was destroyed during the Second World War, the majestic 18th century Residenz palace stands as a testament to the wealth of the bishopric.

The quaint little Bavarian town of Miltenberg sits on the Main river to the southeast of Frankfurt, with a beautiful old town that survived the Second World War unscathed. Timber-framed buildings lean at jaunty angles overhead, not least in the ‘Black Quarter’, where the streets are so narrow that the sunlight barely reaches ground level.

The Rhine and Main rivers meet at Mainz, a friendly university town with a charming cobbled old town and an impressive cathedral. The city was also the home of the first ever printing press, a heritage that you can explore at the fascinating Gutenberg Museum.

Strasbourg is the capital of France’s Alsace region, right next to the border with Germany, and there is a tangible Germanic influence that sets the city a little apart from the rest of France. Highlights include the beautiful Gothic cathedral, the old town’s fairytale half-timbered houses, and the pictureque canals of the Petite France district.

Breisach is a small town on the western fringe of the Black Forest, separated from the French region of Alsace by a bend in the river Rhine. This proximity to France is reflected in a vibrant food and wine scene, and architectural highlights include the hilltop St Stephen's cathedral.