Antwerp is a city bound up with the arts, once home to the likes of Rubens and Van Dyck, and more recently carving out a reputation as the fashion capital of Belgium. It’s also a magnet for shopaholics, with designer boutiques and jewellers galore.

Boppard is one of the most attractive towns on the Rhine, situated on a horseshoe bend with a lovely riverside promenade. Take the chairlift up to the Vierseenblick for fantastic views, go hiking in the woods or explore the pretty streets and handsome architecture of the town itself.

Situated near the confluence of the Rhine and Neckar rivers, Mannheim is an important industrial centre with a lively cultural scene. It’s also conveniently located for exploring the pretty town of Heidelberg and the wine growing region around Nierstein.

Strasbourg is the capital of France’s Alsace region, right next to the border with Germany, and there is a tangible Germanic influence that sets the city a little apart from the rest of France. Highlights include the beautiful Gothic cathedral, the old town’s fairytale half-timbered houses, and the pictureque canals of the Petite France district.

Basel lies where Switzerland, France and Germany meet, a sophisticated and multicultural city with a picturesque setting astride the river Rhine. The medieval Old Town is exceptionally well preserved, best appreciated from the summit of the hilltop cathedral, which offers incredible views across the city.