Renowned for its food, its misty mornings and its vertiginous streets, cosmopolitan San Francisco is quite unlike any other American city. Highlights include the iconic Golden Gate Bridge, the delightful waterfront and the bohemian quarter of Haight Ashbury.

Astoria is the oldest city west of the Rockies, situated on the picturesque Oregon coast where the Columbia river meets the Pacific Ocean. This bustling port town is sometimes known as ‘Little San Francisco’, with handsome Victorian architecture, a proud fishing heritage and a buzzing, creative vibe.

Victoria is the capital of British Columbia and Canada’s westernmost city, with a distinctly English feel that occasionally borders on the twee. It’s a very walkable city, with handsome 19th century architecture, verdant parks and a lively harbour, and, this being Canada, the great outdoors is never far away.

Cosmopolitan Vancouver is a city that rewards exploration, an eminently liveable place and an easy gateway to the natural beauty of British Columbia. The culinary scene here is a particular draw, with seafood galore and some fantastic Asian restaurants.

Ketchikan is a great introduction to Alaska’s natural attractions, situated at the foot of towering Deer Mountain and within easy reach of the Misty Fjords. The colourful wooden buildings of Creek Street, the old red light district, are a reminder of Ketchikan’s former status as a rough and ready frontier town; these days, things are rather more civilised!

Sitka was founded by Russian fur traders in 1799 as the city of New Archangel, and there is still a discernible Russian influence here, including the distinctive St Michael’s Orthodox Cathedral. The town also enjoys spectacular natural surroundings, facing the Pacific Ocean and dramatic Mount Edgecumbe.

The tiny city of Seward, home to just 3,000 people, enjoys a spectacular setting on the edge of Resurrection Bay, on Alaska’s southern coast. Surrounded by the mountains and forests of the Kenai Fjords National Park, it’s a great base for exploring the Harding Ice Field and the stunning scenery of the Kenai Peninsula.

Kodiak is known as Alaska’s ‘Emerald Isle’ thanks to the lush green countryside, a landscape crisscrossed by gushing salmon-filled streams that provides a home to around 3,000 Kodiak bears, the world’s largest. Ships dock in Kodiak city, an important fishing port with a fascinating Russian heritage.

Dutch Harbor is the port that serves the city of Unalaska, and is known for the hardy fishermen who brave the turbulent, icy seas off the Aleutian Islands. Points of interest include the remains of defensive fortifications built during the Second World War and the striking Russian Orthodox church.

The misty fishing port of Kushiro, on the east coast of Hokkaido, is the gateway to the protected marshlands of Kushiro Mitsugen National Park. These extensive wetlands are the only place in Japan where you can still find the endangered Japanese crane, a graceful bird with a distinctive red crown.

Situated at the southern tip of Hokkaido, Hakodate was one of the first Japanese ports to open up to international trade in the 19th century, and a scattering of European-style buildings remain. Take a ride on the historic streetcar, tuck into delicious seafood or enjoy a revitalising dip in an onsen (hot spring).