The Turkish port of Izmir, formerly the Greek city of Smyrna, is a liberal and progressive place where the secularism of Ataturk remains strong. During the Ottoman era this was a melting pot of ethnic groups including Armenians, Jews and Italians, and a cosmopolitan atmosphere persists to this day.

Kos is the second largest of the Dodecanese Islands after Rhodes, and is best known for its excellent beaches. There are plenty of cultural treasures here too: Kos Town’s harbour is guarded by an impressive castle built by the Knights of St John, and the island is scattered with Greek and Roman ruins.

Antalya is the biggest and busiest city on the Turkish Riviera, though there’s more to this place than just roasting on a beach. The historic Kaleiçi district is full of lovingly restored Ottoman mansions, and top attractions include the superb collection of classical treasures at the Antalya Museum, with pieces from the nearby archaeological sites of Perge and Aspendos.

Crete’s bustling capital is a modern and cosmopolitan city, where the island’s rich history isn’t immediately apparent. Take a closer look, however, and you’ll find a fantastic archaeological museum, along with remnants of Venetian fortifications and a lively seafront promenade, with plenty of nice outdoor cafés.

Malta’s tiny capital, established by the Knights of St John, packs in an awful lot of history considering its diminutive size. The atmospheric old streets, bathed in Mediterranean sunshine, are full of attractive honey-golden buildings, along with an impressive selection of bars and restaurants.

Taormina enjoys a truly spectacular setting on Sicily’s east coast, perched on a mountainside looking out towards the smouldering Mount Etna. The medieval streets are pleasant but often crowded in high season, so we’d recommend getting out and exploring the surrounding countryside.

The lovely town of Sorrento, draped across rugged cliffs overlooking the Bay of Naples, has been charming visitors since the days of the Grand Tour. The Renaissance palaces and many craft shops make Sorrento an attractive destination in its own right, and it’s also a jumping off point for Capri, Pompeii and the Amalfi Coast.

One of the world’s great cities, Rome continues to dazzle and delight visitors with a potent mix of architectural marvels, continent-defining history and buzzing nightlife. The Colosseum, the Vatican and the Forum are among the big ticket items, with the crowds to match, though in truth you will find history around almost every corner.

The picturesque little town of Amalfi was once a major Mediterranean naval power, but a devastating earthquake in 1343 cut the city down in its prime and destroyed most of its historic buildings. These days, of course, Amalfi is best known for the eponymous stretch of stunning coastline on which it sits.

Busy, noisy and a little bit scruffy, Catania is Sicily’s second city, poised perilously in the shadow of Mount Etna. In recent years gentrification has taken hold, and the city’s many beautiful palazzi and baroque churches have been restored to their former glory. Eating out here is also a real treat.

Malta’s tiny capital, established by the Knights of St John, packs in an awful lot of history considering its diminutive size. The atmospheric old streets, bathed in Mediterranean sunshine, are full of attractive honey-golden buildings, along with an impressive selection of bars and restaurants.

Rugged Kefalonia is the largest of the Ionian islands, and remains unspoilt by tourism despite earning fame as the setting for ‘Captain Corelli’s Mandolin’. The island rewards exploration, with some splendid beaches and lovely little villages, and the vineyards here produce some excellent wines.

Corfu, known as Kerkyra in Greek, is a beautiful island of verdant hills and rocky coves, and away from the more crowded resorts it remains a sleepy and idyllic place. Don’t miss the picturesque Venetian architecture of Corfu Town, a UNESCO World Heritage Site.

Kotor sits at the head of a beautiful, fjord-like bay, hemmed in by glowering mountains. The compact, walled old town is Montenegro’s star attraction, a warren of little alleyways and shady squares that is often described as a ‘mini Dubrovnik’.

Located on the quieter northern stretch of Croatia’s Dalmatian coast, the walled port city of Zadar is an intriguing blend of old and new, where Roman ruins and psychedelic modern art installations sit alongside one another.

Ravenna is a must-visit for art and history lovers, with an impressive array of UNESCO-listed historic buildings decorated with beautiful Byzantine mosaics. The city is also home to Dante’s tomb, and you’re within easy reach of Bologna, Ferrara and San Marino.

The gritty port city of Rijeka isn’t a huge tourist draw, with most visitors passing through en route to the islands or the neighbouring seaside resort of Opatija, although the city centre is home to some handsome Austro-Hungarian architecture.