Saint John is said to have written the Book of Revelations in a cave on Patmos, and today the spot is marked by the hillside Monastery of the Apocalypse. As well as spirituality, the island is known for its beaches and upmarket vibe, with a scattering of stylish restaurants and bars.

The charming port of Agios Nikolaos, on the north east coast of Crete, offers a beguiling blend of characterful tavernas, lively bars and designer boutiques. The town is centred around little Lake Voulismeni, and nearby attractions include some lovely beaches and the Minoan ruins at Gournia.

The Turkish port of Kusadasi is the gateway to Ephesus, one of the most spectacular archaeological sites in the Eastern Mediterranean. This was the Roman capital of Asia Minor, and the remains constitute the most complete classical city in Europe.

Glamorous Mykonos is the most popular of the Cyclades islands, well known as a haunt of the rich and the famous. It’s also the gateway to the nearby island of Delos, home to one of the most important archaeological sites in Greece.

Sunseekers have long sought out Skiathos for its beautiful beaches, and it’s a great place to spend a day just chilling out mid-way through a cruise. If the beach doesn’t appeal then Skiathos Town is worth exploring, with plenty of restaurants, tavernas and souvenir shops.

The Aegean island of Bozcaada, also known as Tenedos, is a popular weekend and summer escape for residents of Istanbul. The main settlement, Bozcaada Merkez, has an atmospheric Greek quarter full of colourful houses, while elsewhere on the island you'll find vineyards, beaches and an impressive castle.

Istanbul is the place where East meets West, where Asia Minor reaches out across the Bosphorus and almost touches Europe, and the city remains a bristling, bustling cultural melting pot, the skyline dotted with magnificent minarets and domes.

Limnos is off the beaten track, with a refreshingly low key approach to tourism compared to other Greek islands. Ascend the ruins of the Venetian castle for the best views of the island’s beautiful volcanic landscapes, or spend some time wandering around the charming harbourside capital, Myrina.

The resort town of Cesme is situated at the western tip of mainland Turkey on the Aegean coast, renowned for its sandy beaches and crystal clear water. The town is well-equipped for tourists, with smart shops, restaurants and thermal spas, and the impressive Genoese castle merits a visit.

Bodrum is one of the trendiest destinations on Turkey’s Aegean coast, with plenty of private yachts bobbing alongside the traditional gulet boats in the harbour. Whitewashed buildings draped in bougainvillea give the town a Greek feel, overlooked by the imposing 15th century crusader castle.

Sun-kissed Rhodes, the largest of the Dodecanese islands, is steeped in history; the medieval heart of Rhodes Town was once home to the crusading Knights of St John, and later fell to the Ottoman sultan Suleiman the Magnificent. The hillside village of Lindos, with its pretty whitewashed houses, is another highlight.

The volcanic island of Santorini (known officially as Thira) is one of the most spectacularly beautiful in the Mediterranean. The pretty village of Oia, with its whitewashed houses and windmills tumbling down the hillside, is particularly photogenic.

The island of Spetses lies just off the coast of the Peloponnese, and is popular as a second home for well-to-do Athenians. Wander the streets of charming Spetses Town and you’ll find some excellent restaurants, while the surrounding countryside is a verdant landscape of pine forest and gently rolling hills.

Athens is a city awash with historical and cultural significance, but it's much more than an open air museum; this is a dynamic, bustling metropolis, and a place where history is still very much unfolding.

The beautiful Byzantine town of Monemvasia is dramatically located on a steep chunk of rock, originally a coastal headland until an earthquake in AD 375 turned it into an island. Nowadays access is via a narrow causeway, and the pretty streets of the medieval citadel are home to more churches than people.

The little seaside town of Katakolon, on the western coast of the Peloponnese, is the gateway to ancient Olympia, birthplace of the Games and the place where the Olympic flame begins its journey every four years. Make the most of your visit with a guided tour of the ruins, and don’t miss the treasures of the Archaeological Museum.

The pretty town of Parga sits on the Ionian coast of northwest Greece, on a sandy bay between two rocky outcrops. The pastel-coloured houses and lively seafront tavernas make this a pleasant place to spend some time, and points of historical interest include the hilltop Venetian castle.

The port of Brindisi sits at the end of the old Via Appia, and was once an important transit point for pilgrims and crusading knights heading east to the Holy Land. Brindisi's compact old town is pleasant enough, but you may prefer to head inland to visit the stunning baroque city of Lecce.

We never fail to be moved when we see the terracotta roofs and honey-golden walls of Dubrovnik, and a stroll around the perfectly preserved old town is a highlight of any visit to the Dalmatian coast. Make sure you take the time to walk around the walls and soak up the marvellous sea views.

Located on the quieter northern stretch of Croatia’s Dalmatian coast, the walled port city of Zadar is an intriguing blend of old and new, where Roman ruins and psychedelic modern art installations sit alongside one another.